뇌질환의 혁신, 뉴로벤티(NeuroVenti)

R&D SERVICES

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Non-clinical CDRO service

From early-stage discovery to clinical candidate

Animal models for neurological disorders

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Depression 우울증
  • RS, UCMS
  • Social stress: Social isolation, social defeat stress
  • Maternal deprivation
  • Corticosterone/LPS-injection
 AD/Dementia 알츠하이머병
  • Aβ/scopolamine/LPS injection
  • DM-induced dementia model
  • BCCAO
  • Genetic: 5xFAD Tg mice
 PD 파킨슨병
  • 6-OHDA/rotenone/MPTP
  • α-synuclein overexpression
  • α-synuclein PFF
  • A53T Tg mice
 Epilepsy 뇌전증
  • Electricity induced model (MES)
  • Chemical induced model (PTZ, KA, Pilo)
  • Kindling
  • Febrile sz
  • Audiogenic sz
  • Sz-prone animals
ADHD ADHD
  • Genetic: SHR, Fmr1 KO
  • Chemical: EtOH/MK-801-injection
 ASD 자폐증
  • Genetic : CNTNAP2 KO, Fmr1 KO mice, AGMAT Tg mice
  • Chemical : VPA/Poly(I:C)-injection
 Stroke 뇌졸증
  • Photothrombosis-induced model, MCAO
  • ET-1/ Hemin/ autologous blood injection
 Schizophrenia 조현병
  • MK-801/ PCP/amphetamine
  • Poly (I:C)- injection
  • Social stress model (social isolation, social defeat)
 pain 조현병
  • SNL(sciatic nerve ligation)
  • CFA, Formalin injection
  • Acetic acid injection

Automated system for in vivo efficacy & PoC evaluation

in vivo evaluation system for efficacy and adverse effects(AI-based 3D automated behavioral analysis system)

3D Behavior Analysis Observation Equipment
Multi-object simultaneous analysis equipment, researcher simultaneous observation equipment
Ethovision Analysis System
Behavior domain Evaluation method Behavior domain Evaluation method
Sociability & communication
  • Three chamber test
  • Home-cage social test
  • Ultra sonic vocalization test
 Learning & memory
  • Barnes maze test
  • Y-maze test
  • Novel object recognition test
  • Passive avoidance test
  • Morris water maze test
Depression & anxiety
  • Forced swim test
  • Tail suspension test
  • Sucrose preference test
  • Open field test
  • Novelty suppressed feeding test
  • Elevated plus maze test
  • Light dark box test
 Motor function
  • Open field test
  • Rotarod test
  • Footprint test
  • Beam walking test
  • Grip strength test
  • Grid hanging test
  • Pole test
  • Cylinder test
  • Grid waking test
  • Rotation test
Repetitive behavior
  • Self-grooming test
  • Marble-burying test
  • Nest building test
 Impulsivity
  • Cliff avoidance test
  • 5-choice serial reaction time test
  • Delayed discounting test
Behavior domain Experimental technique
Addiction
  • Conditioned place preference test
  • Self administration test
Sleep disturbance
  • Sleeping onset/duration test
  • Electroencephalogram
Sensory-motor gating
  • Prepulse Inhibition test
Seizure
  • Seizure scoring
  • EEG

Verification and Evaluation of Side Effects of CNS

Prepulse inhibition test

Prepulse inhibition test

CPP/SA test

CPP/SA test

Sleep disturbance

Sleep disturbance

Seizure

Growth retardation/FOB
Evaluation Domain Evaluation method Evaluation Domain Evaluation method
Dependence
  • Evaluation of conditional place preferences
  • Self-administered test
 Sleep disorder
  • Sleep test (measurement of sleep time and sleep duration)
  • Brainwave measurement(EEG telemetry)
Sensory exercise gating
  • Antecedent stimulation suppression test
 Convulsions
  • Chemical induced seizure
  • Electricity induced seizure
  • Threshold
  • Brainwave measurement(EEG telemetry)

Evaluation system for in vitro efficacy & MOA

Testing Category Evaluation methodology
Primary cell culture model
  • Primary neurons/astrocytes/microglia culture
  • Neuronal precursor cell culture
  • Primary rat DRG neurons
  • Organotypic brain slice culture
Cell lines
  • HT22, Neuro2A, N27, SH-SY5Y, PC12, C6 glioma, BV-2, bEnd.3 cell, PC12
Neuronal cell death & neurite outgrowth
  • Incucyte zoom live cell imaging system
Mitochondrial function
  • OCR : Seahorse XF Cell Mito Stress Analyzer system
  • Fusion/Fission : ICC (Drp1 and PGC1alpha)
  • Biogenesis : TIMM23, TOMM20, SDHA, COX4, PDK4, SMAC expression, mtDNA
  • ROS : mitoSOX, Mitotracker, TMRM
Neurotransmitter change, Receptor Binding
  • Fast scan cyclic voltammetry
  • Functional reuptake assay(NET, SERT, DAT)
  • Receptor Binding Analysis
  • Binding Prediction
Synaptogenesis & synaptic change
  • Morphology: EM, Confocal Imaging
  • Alternation of synapse protein: WB, IHC/ICC (PSD95, synaptophysin, synapsin, SNARE etc)
Neurogenesis & differentiation
  • Proliferation: Immunostaining(Ki-67, BrdU, Nestin, doublecortin)
  • Differentiation: tPA/PAI-1/MMPs zymography system, Immunostaining(Tuj-1, NCAM, BDNF)
BBB permeability & breakdown
  • Immunostaining: Tight junction molecules, GFAP, vWF, NG2, PDGF
  • BBB integrity: Evans blue dye/IgG extravasation, brain edema
Antioxidant & neuroinflammation
  • Antioxidant enzyme: HO-1, GSH, NQO1
  • ROS measurement: DHE, DCFH2DA, MDA, 4-HNE
  • Expression and release of Inflammatory cytokine: RT-PCR, WB, ELISA
Discovery of New target
  • RNA Sequencing, PCR Array, Epigenome analysis, Real time-PCR, Big-Data Analysis

Assessment system for Dependence and Addiction

Test area Evaluation method Test drug
Receptor binding
  • Dopamine receptor binding assay
  • dopamine reuptake assay
  • GABA receptor binding test
  • chloride ion uptake assay
  • Norepinephrine and serotonin reuptake assay
  • μ, δ, κ-receptor binding test
  • Receptor binding test for CB1, CB2
  • Stimulant
  • depressant
  • hypnotics
  • anesthetics
  • Anti-anxiety & antidepressant
  • opioids
  • cannabinoids
Psychological dependence
  • Conditioned place preference test
  • Self administration test
Physical dependence
  • Spontaneous momentum test(Locomotor test, Prepulse inhibition test, Treadmill test)
  • seizure, Cylinder test
  • Climbing test(dopamine)
  • Head twitch test(serotonin)
  • withdrawal behaviors(Rotarod test, Open field test, Elevated plus maze test)
Withdrawal symptoms
  • Anxiety (Elevated plus maze test)
  • cognition (Novel object recognition test)
  • depression (Forced swim test)
  • Prepulse inhibition test
Drug discrimination
  • drug discrimination test
Sleep disturbance
  • Sleeping test(Pentobarbital-induced sleep model, Caffeine-induced sleep disturbance model, REM sleep deprivation model)
  • EEG
Sensitivity
  • Anhedonia(Sucrose preference test)
Seizure
  • Seizure intensity
  • Time of seizure onset
  • convulsion duration
  • recovery time
  • seizure behavior
  • Electrically-induced model
  • chemically-induced model
  • EEG


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NeuroVenti, Inc. 3rd FL, 37, Bongeunsa-ro 51-gil, Gangnam-gu, Seoul, 06100, Republic of Korea
TEL : 82-2-540-5630 FAX : 82-2-548-5630 E-mail : contact@neuroventi.com

Copyright © 2026 NeuroVenti, Inc. All Rights Reserved.

Business registration number: 181-86-00128, CEO: Chan Young Shin, CEO: Dong-Churl Seo

Privacy Policy

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Notice on the Collection and Use of Personal Information

NeuroVenti Co., Ltd. (hereinafter referred to as the "Company") establishes and discloses the following Privacy Policy to protect the personal information of data subjects and to handle related grievances promptly and smoothly, in accordance with Article 30 of the Personal Information Protection Act. The Company collects the minimum amount of personal information necessary to provide accurate and sincere responses to customer inquiries. We hereby notify you regarding the collection and use of personal information as follows, so please read carefully and agree.

1. Items of Personal Information
Collected The Company collects the following personal information:
- Collected Items: Organization Name, Name, Contact Information, Email Address
- Method of Collection: Website

2. Purpose of Collection and Use of Personal Information
The personal information being processed will not be used for any purpose other than the following. If the purpose of use changes, necessary measures, such as obtaining separate consent in accordance with Article 18 of the Personal Information Protection Act, will be implemented.
- Partner inquiries, test requests, general inquiries
- Contact for verification of inquiries, fact-finding, notifications, and notification of processing results

3. Rights of Data Subjects and How to Exercise Them
Data subjects may exercise their rights to access, correct, delete, suspend processing, request transfer, or object to the processing of their personal information at any time. These rights may be exercised by contacting the Company’s Chief Privacy Officer via written document, telephone, or email. The Company will take prompt and appropriate action within 10 days of receiving the request.

4. Processing and Retention Period of Personal Information
The Company shall promptly and properly destroy personal information once the purpose of use has been achieved or after the retention period (1 year) based on internal policies has elapsed. The destruction procedure involves permanently deleting electronic files in a way that makes recovery impossible, and shredding paper documents.

5. Provision of Personal Information to Third Parties
The Company processes the personal information of data subjects only within the scope specified in the Purpose of Collection and Use. Personal information is provided to third parties only when it falls under Articles 17 and 18 of the Personal Information Protection Act, such as with the consent of the data subject or under special provisions of the law. Furthermore, when providing information to third parties, the Company enters into consignment contracts that include clauses on compliance with personal information protection laws and restrictions on re-consignment.

6. Rejection of Unauthorized Collection of Email Addresses
This website refuses the unauthorized collection of posted email addresses using email collection programs or other technical devices. Please be advised that violations of this may result in criminal punishment under relevant laws.

7. Right to Refuse Consent and Disadvantages of Refusal
You have the right to refuse consent to the collection and use of your personal information. However, if you do not agree to the collection and use of mandatory items, the reception of your inquiry and the use of related services may be restricted.

8. Chief Privacy Officer
The Company assumes overall responsibility for personal information processing tasks and has designated a Chief Privacy Officer to handle complaints and remedial compensation for data subjects related to personal information processing.
- Chief Privacy Officer: CEO Dong-churl SEO (02-540-5630)

9. Remedies for Infringement of Rights
Data subjects may contact the following organizations for damage relief or consultation regarding personal information infringement:

- Personal Information Infringement Report Center: www.118.or.kr (+82-2-118)
- Personal Information Protection Mark Certification Committee: www.privacy.or.kr (+82-2-580-0533~4)
- Supreme Prosecutors' Office, Cyber Investigation Division: www.spo.go.kr (+82-2-3480-2000)
- National Police Agency, Cyber Terror Response Center: www.ctrc.go.kr (+82-2-392-0330)

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